Amidated pleurocidin peptide encapsulated in biodegradable poly(lactide-co-glycolide) microparticles sustains its antibacterial activity against Photobacterium damselae subsp piscicida in cobia

Here's a concise summary of the text: Photobacterium damselae subsp. piscicida (PDP) poses a significant threat to cobia aquaculture, leading to high mortality rates. Overuse of antibiotics raises concerns about bacterial resistance and environmental impact. This study explores pleurocidin (PLE), an antimicrobial peptide, as an alternative treatment. Encapsulation in PLG microparticles enables sustained release and effective protection against PDP infection, demonstrating its potential as an antibacterial agent for cobia farming. Let me know if you need further refinements!